Human Protein Science
Acute kidney injury (AKI) is a common clinical syndrome and an independent risk factor of chronic kidney disease and end-stage renal failure. At present, the treatments of AKI are still very limited and the morbidity and mortality of AKI are rising. Non-coding RNAs (ncRNAs), including microRNAs, long non-coding RNAs and circular RNAs (circRNAs), are RNAs … Read more
A radioimmunoassay (RIA) methodology for progesterone has been developed. It has been validated for the willpower of progesterone in cow skim milk. The foremost reagents used in the event work had been ready and characterised in-house. The assay makes use of a radioiodinated tracer purified by gel filtration on Sephadex G-25, requirements ready in skim … Read more
Trichuriasis is without doubt one of the most typical uncared for tropical illnesses of the world’s poorest individuals. A recombinant vaccine composed of Tm-WAP49, an immunodominant antigen secreted by grownup Trichuris stichocytes into the mucosa of the cecum to which the parasite attaches, is underneath growth. The prototype is being evaluated in a mouse mannequin of Trichuris muris an infection, … Read more
Here, we aimed to evaluate the clinical performance of a novel automated immunoassay HISCL SARS-CoV-2 Antigen assay kit designed to detect the nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This kit comprises automated chemiluminescence detection systems. Western blot analysis confirmed that anti-SARS-CoV antibodies detected SARS-CoV-2N proteins. The best cut-off index was … Read more
Type 1 diabetes (T1D) is an autoimmune illness characterised by destruction of pancreatic β cells. One of the promising therapeutic approaches in T1D is the transplantation of islets; nevertheless, it has critical limitations. To tackle these limitations, immunotherapeutic methods have targeted on restoring immunologic tolerance, stopping transplanted cell destruction by sufferers’ personal immune system. Macrophage-derived … Read more