Challenges and Opportunities for Therapeutic Targeting of Calmodulin Kinase II in Heart.

Challenges and Opportunities for Therapeutic Targeting of Calmodulin Kinase II in Heart.

Heart failure stays a significant well being burden around the globe. Despite nice progress in delineation of molecular mechanisms underlying growth of illness, normal remedy has not superior on the similar tempo. The multifunctional signaling molecule Ca2+/calmodulin-dependent┬áprotein┬ákinase II (CaMKII) has acquired appreciable consideration over current years for its central function in maladaptive reworking and arrhythmias … Read more