Energy metabolism disorder is one of the causes of Parkinson’s disease (PD). Rodents such as rats and mice are often used to establish animal models of PD. This paper uses bibliometric methods to analyze studies of rats and mice models of PD published between 2009 and 2018 in the Web of Science (WOS) database using software CiteSpace V.
In addition, we conducted a literature review on the status of development and research hotspots in this field in 10 articles Related years.The last in mice and rat PD models derived from the database WOS, and keyword analysis in this article is done using CiteSpace V. A timeline graph developed by software to indicate a focus of researchers in total PD field.A of 8636 articles obtained.
The results of cluster analysis in the field of PD such as nerve inflammation, oxidative stress and autophagy contributes to a systematic review of the pathogenesis of PD. At the same time, based on the properties of the drug model, this review has summarized and compared the different administration techniques and mechanisms of 6- hydroxydopamine (6-OHDA), 1-methyl-4-phenyl-1, 2, 4, 5 -tetrahydropyridine (MPTP), paraquat and rotenone.According for bibliometric analysis, the study of PD is focused on the mechanism of oxidative stress, neuroinflammation and autophagy.
Activated microglia release inflammatory cytokines; Mitochondrial dysfunction caused by oxidative damage to mitochondrial proteins; normal autophagy-lysosomal pathway can lead to abnormal protein deposition in dopaminergic neurons. In addition, although many animal models of PD have been established, there are some limitations to this model. Therefore, it is necessary to develop models that accurately mimic human PD.
DCTN3 siRNA |
20-abx913699 |
Abbexa |
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DCTN3 siRNA |
20-abx913700 |
Abbexa |
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DCTN3 Antibody |
1-CSB-PA921442 |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300 |
DCTN3 Antibody |
1-CSB-PA210409 |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300 |
DCTN3 Antibody |
1-CSB-PA006566ESR1HU |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
DCTN3 Antibody |
1-CSB-PA006566ESR2HU |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
DCTN3 Antibody |
1-CSB-PA006566LA01HU |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
anti-DCTN3 |
YF-PA17547 |
Abfrontier |
50 ul |
EUR 435.6 |
Description: Mouse polyclonal to DCTN3 |
anti-DCTN3 |
YF-PA17548 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to DCTN3 |
DCTN3 Conjugated Antibody |
C36403 |
SAB |
100ul |
EUR 476.4 |
DCTN3 cloning plasmid |
CSB-CL006566HU-10ug |
Cusabio |
10ug |
EUR 279.6 |
|
Description: A cloning plasmid for the DCTN3 gene. |
DCTN3 Blocking Peptide |
DF8351-BP |
Affbiotech |
1mg |
EUR 234 |
DCTN3 Polyclonal Antibody |
A57037-020 |
EpiGentek |
20 ul |
EUR 117.7 |
DCTN3 Polyclonal Antibody |
A57037-050 |
EpiGentek |
50 ul |
EUR 302.5 |
DCTN3 Polyclonal Antibody |
A57037-100 |
EpiGentek |
100 ul |
EUR 423.5 |
DCTN3 Polyclonal Antibody |
A57037 |
EpiGentek |
-
EUR 684.66
-
EUR 117.70
-
EUR 302.50
-
EUR 423.50
|
- 100 µg
- 20 ul
- 50 ul
- 100 ul
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Human DCTN3 shRNA Plasmid |
20-abx957717 |
Abbexa |
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Mouse DCTN3 shRNA Plasmid |
20-abx974349 |
Abbexa |
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DCTN3 Antibody, HRP conjugated |
1-CSB-PA006566LB01HU |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
DCTN3 Antibody, FITC conjugated |
1-CSB-PA006566LC01HU |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
DCTN3 Antibody, Biotin conjugated |
1-CSB-PA006566LD01HU |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
DCTN3 Recombinant Protein (Human) |
RP008860 |
ABM |
100 ug |
Ask for price |
DCTN3 Recombinant Protein (Rat) |
RP197492 |
ABM |
100 ug |
Ask for price |
DCTN3 Recombinant Protein (Mouse) |
RP128180 |
ABM |
100 ug |
Ask for price |
DCTN3 Recombinant Protein (Mouse) |
RP128183 |
ABM |
100 ug |
Ask for price |
Dynactin Subunit 3 (DCTN3) Antibody |
abx149748-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
Dynactin Subunit 3 (DCTN3) Antibody |
20-abx210222 |
Abbexa |
|
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Dynactin Subunit 3 (DCTN3) Antibody |
20-abx210223 |
Abbexa |
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Dynactin Subunit 3 (DCTN3) Antibody |
20-abx321092 |
Abbexa |
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Dynactin Subunit 3 (DCTN3) Antibody |
20-abx321093 |
Abbexa |
|
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Dynactin Subunit 3 (DCTN3) Antibody |
20-abx301171 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
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Dynactin Subunit 3 (DCTN3) Antibody |
abx431970-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
Dynactin Subunit 3 (DCTN3) Antibody |
abx431971-200ul |
Abbexa |
200 ul |
EUR 343.2 |
|
Human Dynactin subunit 3 (DCTN3) |
1-CSB-EP006566HU |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Dynactin subunit 3(DCTN3) expressed in E.coli |
Polyclonal DCTN3 Antibody (internal region) |
APG00714G |
Leading Biology |
0.1mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications: |
Polyclonal DCTN3 Antibody (internal region) |
APG00715G |
Leading Biology |
0.1mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications: |
Dctn3 ORF Vector (Rat) (pORF) |
ORF065832 |
ABM |
1.0 ug DNA |
EUR 607.2 |
DCTN3 ORF Vector (Human) (pORF) |
ORF002954 |
ABM |
1.0 ug DNA |
EUR 114 |
Dctn3 ORF Vector (Mouse) (pORF) |
ORF042728 |
ABM |
1.0 ug DNA |
EUR 607.2 |
Dctn3 ORF Vector (Mouse) (pORF) |
ORF042729 |
ABM |
1.0 ug DNA |
EUR 607.2 |
DCTN3 Polyclonal Antibody, HRP Conjugated |
A57038-050 |
EpiGentek |
50 ul |
EUR 302.5 |
DCTN3 Polyclonal Antibody, HRP Conjugated |
A57038-100 |
EpiGentek |
100 ul |
EUR 423.5 |
DCTN3 Polyclonal Antibody, FITC Conjugated |
A57039-050 |
EpiGentek |
50 ul |
EUR 302.5 |
DCTN3 Polyclonal Antibody, FITC Conjugated |
A57039-100 |
EpiGentek |
100 ul |
EUR 423.5 |
DCTN3 Polyclonal Antibody, Biotin Conjugated |
A57040-050 |
EpiGentek |
50 ul |
EUR 302.5 |
DCTN3 Polyclonal Antibody, Biotin Conjugated |
A57040-100 |
EpiGentek |
100 ul |
EUR 423.5 |
DCTN3 Polyclonal Antibody, HRP Conjugated |
A57038 |
EpiGentek |
-
EUR 684.66
-
EUR 302.50
-
EUR 423.50
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|
DCTN3 Polyclonal Antibody, FITC Conjugated |
A57039 |
EpiGentek |
-
EUR 684.66
-
EUR 302.50
-
EUR 423.50
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|
DCTN3 Polyclonal Antibody, Biotin Conjugated |
A57040 |
EpiGentek |
-
EUR 684.66
-
EUR 302.50
-
EUR 423.50
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Human Dynactin 3 (DCTN3)ELISA Kit |
201-12-2661 |
SunredBio |
96 tests |
EUR 528 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Dynactin Subunit 3 (DCTN3) Antibody (HRP) |
20-abx303590 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
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Dynactin Subunit 3 (DCTN3) Antibody (FITC) |
20-abx303591 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Dynactin Subunit 3 (DCTN3) Antibody (Biotin) |
20-abx303592 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
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DCTN3 sgRNA CRISPR Lentivector set (Human) |
K0567401 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Dctn3 sgRNA CRISPR Lentivector set (Rat) |
K6032901 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Dctn3 sgRNA CRISPR Lentivector set (Mouse) |
K3108201 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Bovine Dynactin subunit 3, DCTN3 ELISA KIT |
ELI-26525b |
Lifescience Market |
96 Tests |
EUR 1113.6 |
Human Dynactin subunit 3, DCTN3 ELISA KIT |
ELI-08944h |
Lifescience Market |
96 Tests |
EUR 988.8 |
DCTN3 sgRNA CRISPR Lentivector (Human) (Target 1) |
K0567402 |
ABM |
1.0 ug DNA |
EUR 184.8 |
DCTN3 sgRNA CRISPR Lentivector (Human) (Target 2) |
K0567403 |
ABM |
1.0 ug DNA |
EUR 184.8 |
DCTN3 sgRNA CRISPR Lentivector (Human) (Target 3) |
K0567404 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Dctn3 sgRNA CRISPR Lentivector (Rat) (Target 1) |
K6032902 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Dctn3 sgRNA CRISPR Lentivector (Rat) (Target 2) |
K6032903 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Dctn3 sgRNA CRISPR Lentivector (Rat) (Target 3) |
K6032904 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Dctn3 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K3108202 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Dctn3 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K3108203 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Dctn3 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K3108204 |
ABM |
1.0 ug DNA |
EUR 184.8 |
DCTN3 Protein Vector (Human) (pPB-C-His) |
PV011813 |
ABM |
500 ng |
EUR 394.8 |
DCTN3 Protein Vector (Human) (pPB-N-His) |
PV011814 |
ABM |
500 ng |
EUR 394.8 |
DCTN3 Protein Vector (Human) (pPM-C-HA) |
PV011815 |
ABM |
500 ng |
EUR 394.8 |
DCTN3 Protein Vector (Human) (pPM-C-His) |
PV011816 |
ABM |
500 ng |
EUR 394.8 |
DCTN3 Protein Vector (Mouse) (pPB-C-His) |
PV170910 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Mouse) (pPB-N-His) |
PV170911 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Mouse) (pPM-C-HA) |
PV170912 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Mouse) (pPM-C-His) |
PV170913 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Mouse) (pPB-C-His) |
PV170914 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Mouse) (pPB-N-His) |
PV170915 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Mouse) (pPM-C-HA) |
PV170916 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Mouse) (pPM-C-His) |
PV170917 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 3'UTR Luciferase Stable Cell Line |
TU005639 |
ABM |
1.0 ml |
EUR 1672.8 |
Dctn3 3'UTR GFP Stable Cell Line |
TU253211 |
ABM |
1.0 ml |
Ask for price |
Dctn3 3'UTR Luciferase Stable Cell Line |
TU104917 |
ABM |
1.0 ml |
Ask for price |
DCTN3 3'UTR GFP Stable Cell Line |
TU055639 |
ABM |
1.0 ml |
EUR 1672.8 |
Dctn3 3'UTR Luciferase Stable Cell Line |
TU203211 |
ABM |
1.0 ml |
Ask for price |
Dctn3 3'UTR GFP Stable Cell Line |
TU154917 |
ABM |
1.0 ml |
Ask for price |
DCTN3 Protein Vector (Rat) (pPB-C-His) |
PV263326 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Rat) (pPB-N-His) |
PV263327 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Rat) (pPM-C-HA) |
PV263328 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 Protein Vector (Rat) (pPM-C-His) |
PV263329 |
ABM |
500 ng |
EUR 723.6 |
DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
K0567405 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat) |
K6032905 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
K3108205 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
K0567406 |
ABM |
1.0 ug DNA |
EUR 200.4 |
DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
K0567407 |
ABM |
1.0 ug DNA |
EUR 200.4 |
DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
K0567408 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1) |
K6032906 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2) |
K6032907 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3) |
K6032908 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
K3108206 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
K3108207 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
K3108208 |
ABM |
1.0 ug DNA |
EUR 200.4 |