Bibliometrics and Visualization of the Mechanisms of Parkinson’s Diseases based on Animal Models.

Energy metabolism disorder is one of the causes of Parkinson’s disease (PD). Rodents such as rats and mice are often used to establish animal models of PD. This paper uses bibliometric methods to analyze studies of rats and mice models of PD published between 2009 and 2018 in the Web of Science (WOS) database using software CiteSpace V.

In addition, we conducted a literature review on the status of development and research hotspots in this field in 10 articles Related years.The last in mice and rat PD models derived from the database WOS, and keyword analysis in this article is done using CiteSpace V. A timeline graph developed by software to indicate a focus of researchers in total PD field.A of 8636 articles obtained.

The results of cluster analysis in the field of PD such as nerve inflammation, oxidative stress and autophagy contributes to a systematic review of the pathogenesis of PD. At the same time, based on the properties of the drug model, this review has summarized and compared the different administration techniques and mechanisms of 6- hydroxydopamine (6-OHDA), 1-methyl-4-phenyl-1, 2, 4, 5 -tetrahydropyridine (MPTP), paraquat and rotenone.According for bibliometric analysis, the study of PD is focused on the mechanism of oxidative stress, neuroinflammation and autophagy.

Activated microglia release inflammatory cytokines; Mitochondrial dysfunction caused by oxidative damage to mitochondrial proteins; normal autophagy-lysosomal pathway can lead to abnormal protein deposition in dopaminergic neurons. In addition, although many animal models of PD have been established, there are some limitations to this model. Therefore, it is necessary to develop models that accurately mimic human PD.

DCTN3 Peptide
42-330P 0.1 mg
EUR 405.6
Description: (IN) DCTN3 Peptide

DCTN3 Peptide
42-682P 0.1 mg
EUR 405.6
Description: (IN) DCTN3 Peptide

DCTN3 Antibody
36403 100ul
EUR 319

DCTN3 Antibody
36403-100ul 100ul
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DCTN3 Antibody
ABD8351 100 ug
EUR 525.6

DCTN3 Antibody
1-CSB-PA006566ESR1HU
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  • 100ul
  • 50ul
Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

DCTN3 Antibody
1-CSB-PA006566ESR2HU
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  • 100ul
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

DCTN3 Antibody
1-CSB-PA006566LA01HU
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  • 50ug
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

DCTN3 Antibody
DF8351 200ul
EUR 420

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DF8351-100ul 100ul
EUR 168
Description: WB,IHC,ELISA(peptide)

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EUR 210
Description: WB,IHC,ELISA(peptide)

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1-CSB-PA210409
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  • 50ul
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300

DCTN3 Antibody
CAC11828-100ug 100ug
EUR 314

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CAC11828-50ug 50ug
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C43401-100ul 100μl
EUR 217
Description: DCTN3 Rabbit Polyclonal Antibody

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Description: DCTN3 Rabbit Polyclonal Antibody

DCTN3 Antibody
1-CSB-PA921442
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300

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GWB-MW590E 50ug Ask for price

DCTN3 Antibody
E036403 100μg/100μl
EUR 255
Description: Available in various conjugation types.

DCTN3 Antibody
E19-8351-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

DCTN3 Antibody
E19-8351-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

DCTN3 Antibody
MBS7044587-005mL 0.05mL
EUR 190

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MBS7044587-01mL 0.1mL
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MBS7044587-5x01mL 5x0.1mL
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MBS7045692-005mL 0.05mL
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MBS7045692-01mL 0.1mL
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MBS7045692-5x01mL 5x0.1mL
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MBS7125431-005mL 0.05mL
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MBS7125431-01mL 0.1mL
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MBS7125431-5x01mL 5x0.1mL
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MBS7125432-005mL 0.05mL
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MBS7125432-01mL 0.1mL
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MBS7125432-5x01mL 5x0.1mL
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DCTN3 Antibody
MBS9608728-01mL 0.1mL
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MBS9608728-02mL 0.2mL
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MBS9608728-5x02mL 5x0.2mL
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DCTN3 Antibody
MBS8517525-005mg 0.05mg
EUR 235

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MBS8517525-01mg 0.1mg
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DCTN3 Antibody
MBS8517525-01mLAF405M 0.1mL(AF405M)
EUR 465

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MBS8517525-01mLAF546 0.1mL(AF546)
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MBS8517525-01mLAF750 0.1mL(AF750)
EUR 465

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MBS9411499-01mL 0.1mL
EUR 305

DCTN3 Antibody
MBS9411499-5x01mL 5x0.1mL
EUR 1230

Dctn3 (untagged ORF) - Rat dynactin 3 (Dctn3), (10 ug)
RN211869 10 µg Ask for price

DCTN3 Rabbit mAb
56772 100ul
EUR 339

DCTN3 Rabbit pAb
A8190 100μL
EUR 70.85

DCTN3 cDNA Clone
MBS1266314-001mgPlasmid02mLGlycerolStock 0.01mgPlasmid+0.2mLGlycerol-Stock
EUR 200

DCTN3 cDNA Clone
MBS1266314-5x001mgPlasmid5x02mLGlycerolStock 5x0.01mgPlasmid+5x0.2mLGlycerol-Stock
EUR 855

DCTN3 rabbit pAb
E28PN3757 100μl
EUR 255
Description: Available in various conjugation types.

DCTN3 rabbit pAb
E44H12641 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

DCTN3 rabbit pAb
UB-GEN-8433 100 ul
EUR 200

Mouse DCTN3 siRNA
20-abx913699
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  • 15 nmol
  • 30 nmol

Human DCTN3 siRNA
20-abx913700
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  • 15 nmol
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DCTN3 siRNA (Mouse)
MBS8206143-15nmol 15nmol
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MBS8206143-30nmol 30nmol
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MBS8206143-5x30nmol 5x30nmol
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MBS8217785-30nmol 30nmol
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MBS8217785-5x30nmol 5x30nmol
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DCTN3 cloning plasmid
CSB-CL006566HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the DCTN3 gene.

DCTN3 Blocking Peptide
DF8351-BP 1mg
EUR 234

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MBS9627440-1mg 1mg
EUR 380

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MBS427704-01mg 0.1mg
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DCTN3 (untagged)-Human dynactin 3 (p22) (DCTN3), transcript variant 1
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DCTN3 Polyclonal Antibody
A57037
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DCTN3 Polyclonal Antibody
E-AB-14937-120uL 120uL
EUR 240
Description: Unconjugated

DCTN3 Polyclonal Antibody
E-AB-14937-200uL 200uL
EUR 399
Description: Unconjugated

DCTN3 Polyclonal Antibody
E-AB-14937-20uL 20uL
EUR 73
Description: Unconjugated

DCTN3 Polyclonal Antibody
E-AB-14937-60uL 60uL
EUR 143
Description: Unconjugated

DCTN3 Polyclonal Antibody
E-AB-11144-120uL 120uL
EUR 240
Description: Unconjugated

DCTN3 Polyclonal Antibody
E-AB-11144-200uL 200uL
EUR 399
Description: Unconjugated

DCTN3 Polyclonal Antibody
E-AB-11144-20uL 20uL
EUR 73
Description: Unconjugated

DCTN3 Polyclonal Antibody
E-AB-11144-60uL 60uL
EUR 143
Description: Unconjugated

DCTN3 Conjugated Antibody
C36403 100ul
EUR 476.4

DCTN3 Polyclonal Antibody
E98190 100ul
EUR 225
Description: Available in various conjugation types.

DCTN3 Polyclonal Antibody
MBS2524877-002mL 0.02mL
EUR 135

DCTN3 Polyclonal Antibody
MBS2524877-006mL 0.06mL
EUR 190

DCTN3 Polyclonal Antibody
MBS2524877-012mL 0.12mL
EUR 265

DCTN3 Polyclonal Antibody
MBS2524877-02mL 0.2mL
EUR 415

DCTN3 Polyclonal Antibody
MBS2524877-5x02mL 5x0.2mL
EUR 1835

DCTN3 Polyclonal Antibody
MBS2525409-002mL 0.02mL
EUR 135

DCTN3 Polyclonal Antibody
MBS2525409-006mL 0.06mL
EUR 190

DCTN3 Polyclonal Antibody
MBS2525409-012mL 0.12mL
EUR 265

DCTN3 Polyclonal Antibody
MBS2525409-02mL 0.2mL
EUR 415

DCTN3 Polyclonal Antibody
MBS2525409-5x02mL 5x0.2mL
EUR 1835

DCTN3 Polyclonal Antibody
MBS8573809-01mL 0.1mL
EUR 305

DCTN3 Polyclonal Antibody
MBS8573809-01mLAF405L 0.1mL(AF405L)
EUR 565

DCTN3 Polyclonal Antibody
MBS8573809-01mLAF405S 0.1mL(AF405S)
EUR 565

DCTN3 Polyclonal Antibody
MBS8573809-01mLAF610 0.1mL(AF610)
EUR 565

DCTN3 Polyclonal Antibody
MBS8573809-01mLAF635 0.1mL(AF635)
EUR 565

DCTN3 Polyclonal Antibody
MBS9238317-01mL 0.1mL
EUR 415

DCTN3 Polyclonal Antibody
MBS9238317-5x01mL 5x0.1mL
EUR 1841

DCTN3 Conjugated Antibody
MBS9446862-01mLAF350 0.1mL(AF350)
EUR 480

DCTN3 Conjugated Antibody
MBS9446862-01mLAF405 0.1mL(AF405)
EUR 480

DCTN3 Conjugated Antibody
MBS9446862-01mLAF488 0.1mL(AF488)
EUR 480

DCTN3 Conjugated Antibody
MBS9446862-01mLAF555 0.1mL(AF555)
EUR 480

DCTN3 Conjugated Antibody
MBS9446862-01mLBiotin 0.1mL(Biotin)
EUR 480

DCTN3 Polyclonal Antibody
RD78012A-120uL 120μL
EUR 360
Description: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

DCTN3 Polyclonal Antibody
RD78012A-200uL 200μL
EUR 630
Description: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

DCTN3 Polyclonal Antibody
RD78012A-20uL 20μL
EUR 109.5
Description: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

DCTN3 Polyclonal Antibody
RD78012A-60uL 60μL
EUR 214.5
Description: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

DCTN3 Polyclonal Antibody
RD75764A-120uL 120μL
EUR 360
Description: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

DCTN3 Polyclonal Antibody
RD75764A-200uL 200μL
EUR 630
Description: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

DCTN3 Polyclonal Antibody
RD75764A-20uL 20μL
EUR 109.5
Description: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

DCTN3 Polyclonal Antibody
RD75764A-60uL 60μL
EUR 214.5
Description: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

Dctn3 (untagged) - Mouse dynactin 3 (Dctn3), transcript variant 1, (10ug)
MC209938 10 µg Ask for price

Dctn3 (untagged) - Mouse dynactin 3 (Dctn3), transcript variant 2, (10ug)
MC209939 10 µg Ask for price

Dctn3 (Myc-DDK-tagged ORF) - Rat dynactin 3 (Dctn3), (10 ug)
RR211869 10 µg Ask for price

DCTN3 (GFP-tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 2
RG201253 10 µg Ask for price

DCTN3 (GFP-tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 1
RG210658 10 µg Ask for price

Dctn3 (GFP-tagged) - Mouse dynactin 3 (Dctn3) transcript variant 2, (10ug)
MG217276 10 µg Ask for price

Dctn3 (Myc-DDK-tagged) - Mouse dynactin 3 (Dctn3), transcript variant 2
MR217276 10 µg Ask for price

Dctn3 (Myc-DDK-tagged) - Mouse dynactin 3 (Dctn3), transcript variant 1
MR201747 10 µg Ask for price

Human DCTN3 shRNA Plasmid
20-abx957717
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  • 150 µg
  • 300 µg