Energy metabolism disorder is one of the causes of Parkinson’s disease (PD). Rodents such as rats and mice are often used to establish animal models of PD. This paper uses bibliometric methods to analyze studies of rats and mice models of PD published between 2009 and 2018 in the Web of Science (WOS) database using software CiteSpace V.
In addition, we conducted a literature review on the status of development and research hotspots in this field in 10 articles Related years.The last in mice and rat PD models derived from the database WOS, and keyword analysis in this article is done using CiteSpace V. A timeline graph developed by software to indicate a focus of researchers in total PD field.A of 8636 articles obtained.
The results of cluster analysis in the field of PD such as nerve inflammation, oxidative stress and autophagy contributes to a systematic review of the pathogenesis of PD. At the same time, based on the properties of the drug model, this review has summarized and compared the different administration techniques and mechanisms of 6- hydroxydopamine (6-OHDA), 1-methyl-4-phenyl-1, 2, 4, 5 -tetrahydropyridine (MPTP), paraquat and rotenone.According for bibliometric analysis, the study of PD is focused on the mechanism of oxidative stress, neuroinflammation and autophagy.
Activated microglia release inflammatory cytokines; Mitochondrial dysfunction caused by oxidative damage to mitochondrial proteins; normal autophagy-lysosomal pathway can lead to abnormal protein deposition in dopaminergic neurons. In addition, although many animal models of PD have been established, there are some limitations to this model. Therefore, it is necessary to develop models that accurately mimic human PD.
DCTN3 Antibody |
1-CSB-PA921442 |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300 |
DCTN3 Antibody |
36403-100ul |
SAB |
100ul |
EUR 252 |
DCTN3 siRNA |
20-abx913699 |
Abbexa |
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DCTN3 siRNA |
20-abx913700 |
Abbexa |
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DCTN3 Antibody |
DF8351 |
Affbiotech |
200ul |
EUR 304 |
Description: DCTN3 Antibody detects endogenous levels of total DCTN3. |
anti-DCTN3 |
YF-PA17547 |
Abfrontier |
50 ul |
EUR 363 |
Description: Mouse polyclonal to DCTN3 |
anti-DCTN3 |
YF-PA17548 |
Abfrontier |
50 ug |
EUR 363 |
Description: Mouse polyclonal to DCTN3 |
DCTN3 Peptide |
42-330P |
ProSci |
0.1 mg |
EUR 338 |
Description: (IN) DCTN3 Peptide |
DCTN3 Peptide |
42-682P |
ProSci |
0.1 mg |
EUR 338 |
Description: (IN) DCTN3 Peptide |
DCTN3 cloning plasmid |
CSB-CL006566HU-10ug |
Cusabio |
10ug |
EUR 233 |
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Description: A cloning plasmid for the DCTN3 gene. |
DCTN3 Polyclonal Antibody |
A57037 |
EpiGentek |
100 µg |
EUR 570.55 |
Description: The best epigenetics products |
DCTN3 Conjugated Antibody |
C36403 |
SAB |
100ul |
EUR 397 |
DCTN3 Blocking Peptide |
DF8351-BP |
Affbiotech |
1mg |
EUR 195 |
DCTN3 Antibody, HRP conjugated |
1-CSB-PA006566LB01HU |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
DCTN3 Antibody, FITC conjugated |
1-CSB-PA006566LC01HU |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
DCTN3 Antibody, Biotin conjugated |
1-CSB-PA006566LD01HU |
Cusabio |
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Mouse DCTN3 shRNA Plasmid |
20-abx974349 |
Abbexa |
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Human DCTN3 shRNA Plasmid |
20-abx957717 |
Abbexa |
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DCTN3 Recombinant Protein (Mouse) |
RP128180 |
ABM |
100 ug |
Ask for price |
DCTN3 Recombinant Protein (Mouse) |
RP128183 |
ABM |
100 ug |
Ask for price |
DCTN3 Recombinant Protein (Rat) |
RP197492 |
ABM |
100 ug |
Ask for price |
DCTN3 Recombinant Protein (Human) |
RP008860 |
ABM |
100 ug |
Ask for price |
Human Dynactin subunit 3 (DCTN3) |
1-CSB-EP006566HU |
Cusabio |
-
EUR 380.00
-
EUR 214.00
-
EUR 1309.00
-
EUR 560.00
-
EUR 873.00
-
EUR 262.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
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Description: Recombinant Human Dynactin subunit 3(DCTN3) expressed in E.coli |
Polyclonal DCTN3 Antibody (internal region) |
APG00714G |
Leading Biology |
0.1mg |
EUR 484 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications: |
Polyclonal DCTN3 Antibody (internal region) |
APG00715G |
Leading Biology |
0.1mg |
EUR 484 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications: |
Dynactin Subunit 3 (DCTN3) Antibody |
20-abx321092 |
Abbexa |
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Dynactin Subunit 3 (DCTN3) Antibody |
20-abx321093 |
Abbexa |
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Dynactin Subunit 3 (DCTN3) Antibody |
abx149748-100ug |
Abbexa |
100 ug |
EUR 439 |
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DCTN3 Polyclonal Antibody, HRP Conjugated |
A57038 |
EpiGentek |
100 µg |
EUR 570.55 |
Description: kits suitable for this type of research |
DCTN3 Polyclonal Antibody, FITC Conjugated |
A57039 |
EpiGentek |
100 µg |
EUR 570.55 |
Description: fast delivery possible |
DCTN3 Polyclonal Antibody, Biotin Conjugated |
A57040 |
EpiGentek |
100 µg |
EUR 570.55 |
Description: reagents widely cited |
Dynactin Subunit 3 (DCTN3) Antibody |
abx431970-200ul |
Abbexa |
200 ul |
EUR 384 |
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Dynactin Subunit 3 (DCTN3) Antibody |
abx431971-200ul |
Abbexa |
200 ul |
EUR 286 |
|
Dynactin Subunit 3 (DCTN3) Antibody |
20-abx210222 |
Abbexa |
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Dynactin Subunit 3 (DCTN3) Antibody |
20-abx210223 |
Abbexa |
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Dynactin Subunit 3 (DCTN3) Antibody |
20-abx301171 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
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EUR 182.00
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EUR 300.00
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- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
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Dctn3 ORF Vector (Mouse) (pORF) |
ORF042728 |
ABM |
1.0 ug DNA |
EUR 506 |
Dctn3 ORF Vector (Mouse) (pORF) |
ORF042729 |
ABM |
1.0 ug DNA |
EUR 506 |
DCTN3 ORF Vector (Human) (pORF) |
ORF002954 |
ABM |
1.0 ug DNA |
EUR 95 |
Dctn3 ORF Vector (Rat) (pORF) |
ORF065832 |
ABM |
1.0 ug DNA |
EUR 506 |
Human Dynactin 3 (DCTN3)ELISA Kit |
201-12-2661 |
SunredBio |
96 tests |
EUR 440 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Dynactin Subunit 3 (DCTN3) Antibody (HRP) |
20-abx303590 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
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Dynactin Subunit 3 (DCTN3) Antibody (FITC) |
20-abx303591 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
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Dynactin Subunit 3 (DCTN3) Antibody (Biotin) |
20-abx303592 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
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Dctn3 sgRNA CRISPR Lentivector set (Mouse) |
K3108201 |
ABM |
3 x 1.0 ug |
EUR 339 |
DCTN3 sgRNA CRISPR Lentivector set (Human) |
K0567401 |
ABM |
3 x 1.0 ug |
EUR 339 |
Dctn3 sgRNA CRISPR Lentivector set (Rat) |
K6032901 |
ABM |
3 x 1.0 ug |
EUR 339 |
Dctn3 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K3108202 |
ABM |
1.0 ug DNA |
EUR 154 |
Dctn3 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K3108203 |
ABM |
1.0 ug DNA |
EUR 154 |
Dctn3 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K3108204 |
ABM |
1.0 ug DNA |
EUR 154 |
DCTN3 sgRNA CRISPR Lentivector (Human) (Target 1) |
K0567402 |
ABM |
1.0 ug DNA |
EUR 154 |
DCTN3 sgRNA CRISPR Lentivector (Human) (Target 2) |
K0567403 |
ABM |
1.0 ug DNA |
EUR 154 |
DCTN3 sgRNA CRISPR Lentivector (Human) (Target 3) |
K0567404 |
ABM |
1.0 ug DNA |
EUR 154 |
Dctn3 sgRNA CRISPR Lentivector (Rat) (Target 1) |
K6032902 |
ABM |
1.0 ug DNA |
EUR 154 |
Dctn3 sgRNA CRISPR Lentivector (Rat) (Target 2) |
K6032903 |
ABM |
1.0 ug DNA |
EUR 154 |
Dctn3 sgRNA CRISPR Lentivector (Rat) (Target 3) |
K6032904 |
ABM |
1.0 ug DNA |
EUR 154 |
DCTN3 Protein Vector (Human) (pPB-C-His) |
PV011813 |
ABM |
500 ng |
EUR 329 |
DCTN3 Protein Vector (Human) (pPB-N-His) |
PV011814 |
ABM |
500 ng |
EUR 329 |
DCTN3 Protein Vector (Human) (pPM-C-HA) |
PV011815 |
ABM |
500 ng |
EUR 329 |
DCTN3 Protein Vector (Human) (pPM-C-His) |
PV011816 |
ABM |
500 ng |
EUR 329 |
DCTN3 Protein Vector (Rat) (pPB-C-His) |
PV263326 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Rat) (pPB-N-His) |
PV263327 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Rat) (pPM-C-HA) |
PV263328 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Rat) (pPM-C-His) |
PV263329 |
ABM |
500 ng |
EUR 603 |
Dctn3 3'UTR Luciferase Stable Cell Line |
TU104917 |
ABM |
1.0 ml |
Ask for price |
DCTN3 Protein Vector (Mouse) (pPB-C-His) |
PV170910 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Mouse) (pPB-N-His) |
PV170911 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Mouse) (pPM-C-HA) |
PV170912 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Mouse) (pPM-C-His) |
PV170913 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Mouse) (pPB-C-His) |
PV170914 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Mouse) (pPB-N-His) |
PV170915 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Mouse) (pPM-C-HA) |
PV170916 |
ABM |
500 ng |
EUR 603 |
DCTN3 Protein Vector (Mouse) (pPM-C-His) |
PV170917 |
ABM |
500 ng |
EUR 603 |
Dctn3 3'UTR GFP Stable Cell Line |
TU253211 |
ABM |
1.0 ml |
Ask for price |
Dctn3 3'UTR Luciferase Stable Cell Line |
TU203211 |
ABM |
1.0 ml |
Ask for price |
DCTN3 3'UTR GFP Stable Cell Line |
TU055639 |
ABM |
1.0 ml |
EUR 1394 |
DCTN3 3'UTR Luciferase Stable Cell Line |
TU005639 |
ABM |
1.0 ml |
EUR 1394 |
Dctn3 3'UTR GFP Stable Cell Line |
TU154917 |
ABM |
1.0 ml |
Ask for price |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
K3108205 |
ABM |
3 x 1.0 ug |
EUR 376 |
DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
K0567405 |
ABM |
3 x 1.0 ug |
EUR 376 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat) |
K6032905 |
ABM |
3 x 1.0 ug |
EUR 376 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
K3108206 |
ABM |
1.0 ug DNA |
EUR 167 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
K3108207 |
ABM |
1.0 ug DNA |
EUR 167 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
K3108208 |
ABM |
1.0 ug DNA |
EUR 167 |
DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
K0567406 |
ABM |
1.0 ug DNA |
EUR 167 |
DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
K0567407 |
ABM |
1.0 ug DNA |
EUR 167 |
DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
K0567408 |
ABM |
1.0 ug DNA |
EUR 167 |
Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1) |
K6032906 |
ABM |
1.0 ug DNA |
EUR 167 |