Bibliometrics and Visualization of the Mechanisms of Parkinson’s Diseases based on Animal Models.

Energy metabolism disorder is one of the causes of Parkinson’s disease (PD). Rodents such as rats and mice are often used to establish animal models of PD. This paper uses bibliometric methods to analyze studies of rats and mice models of PD published between 2009 and 2018 in the Web of Science (WOS) database using software CiteSpace V.

In addition, we conducted a literature review on the status of development and research hotspots in this field in 10 articles Related years.The last in mice and rat PD models derived from the database WOS, and keyword analysis in this article is done using CiteSpace V. A timeline graph developed by software to indicate a focus of researchers in total PD field.A of 8636 articles obtained.

The results of cluster analysis in the field of PD such as nerve inflammation, oxidative stress and autophagy contributes to a systematic review of the pathogenesis of PD. At the same time, based on the properties of the drug model, this review has summarized and compared the different administration techniques and mechanisms of 6- hydroxydopamine (6-OHDA), 1-methyl-4-phenyl-1, 2, 4, 5 -tetrahydropyridine (MPTP), paraquat and rotenone.According for bibliometric analysis, the study of PD is focused on the mechanism of oxidative stress, neuroinflammation and autophagy.

Activated microglia release inflammatory cytokines; Mitochondrial dysfunction caused by oxidative damage to mitochondrial proteins; normal autophagy-lysosomal pathway can lead to abnormal protein deposition in dopaminergic neurons. In addition, although many animal models of PD have been established, there are some limitations to this model. Therefore, it is necessary to develop models that accurately mimic human PD.

DCTN3 Peptide

42-330P 0.1 mg
EUR 405.6
Description: (IN) DCTN3 Peptide

DCTN3 Peptide

42-682P 0.1 mg
EUR 405.6
Description: (IN) DCTN3 Peptide

DCTN3 Antibody

1-CSB-PA921442
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300

DCTN3 Antibody

1-CSB-PA006566ESR1HU
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

DCTN3 Antibody

1-CSB-PA006566ESR2HU
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

DCTN3 Antibody

1-CSB-PA006566LA01HU
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

DCTN3 Antibody

E036403 100μg/100μl
EUR 255
Description: Available in various conjugation types.

DCTN3 Antibody

E19-8351-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

DCTN3 Antibody

E19-8351-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

DCTN3 Antibody

DF8351 200ul
EUR 420

DCTN3 Antibody

DF8351-100ul 100ul
EUR 280

DCTN3 Antibody

DF8351-200ul 200ul
EUR 350

DCTN3 Antibody

36403 100ul
EUR 319

DCTN3 Antibody

36403-100ul 100ul
EUR 302.4

DCTN3 Antibody

ABD8351 100 ug
EUR 525.6

DCTN3 Antibody

CAC11828-100ug 100ug
EUR 314

DCTN3 Antibody

CAC11828-50ug 50ug
EUR 199.2

DCTN3 Antibody

1-CSB-PA210409
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300

DCTN3 Antibody

GWB-MW590E 50ug Ask for price

Dctn3 (untagged ORF) - Rat dynactin 3 (Dctn3), (10 ug)

RN211869 10 µg Ask for price

DCTN3 rabbit pAb

E28PN3757 100μl
EUR 255
Description: Available in various conjugation types.

DCTN3 Rabbit mAb

56772 100ul
EUR 339

DCTN3 rabbit pAb

E44H12641 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

DCTN3 cloning plasmid

CSB-CL006566HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the DCTN3 gene.

DCTN3 Blocking Peptide

DF8351-BP 1mg
EUR 234

DCTN3 (untagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 4

SC334002 10 µg Ask for price

DCTN3 (untagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 3

SC334043 10 µg Ask for price

DCTN3 (untagged)-Human dynactin 3 (p22) (DCTN3), transcript variant 1

SC110250 10 µg Ask for price

DCTN3 (untagged)-Human dynactin 3 (p22) (DCTN3), transcript variant 2

SC110251 10 µg Ask for price

DCTN3 (untagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 5

SC334187 10 µg Ask for price

DCTN3 Polyclonal Antibody

E98190 100ul
EUR 225
Description: Available in various conjugation types.

DCTN3 Polyclonal Antibody

A57037
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DCTN3 Conjugated Antibody

C36403 100ul
EUR 476.4

DCTN3 Polyclonal Antibody

E-AB-14937-120uL 120uL
EUR 240
Description: Unconjugated

DCTN3 Polyclonal Antibody

E-AB-14937-200uL 200uL
EUR 399
Description: Unconjugated

DCTN3 Polyclonal Antibody

E-AB-14937-20uL 20uL
EUR 73
Description: Unconjugated

DCTN3 Polyclonal Antibody

E-AB-14937-60uL 60uL
EUR 143
Description: Unconjugated

DCTN3 Polyclonal Antibody

E-AB-11144-120uL 120uL
EUR 240
Description: Unconjugated

DCTN3 Polyclonal Antibody

E-AB-11144-200uL 200uL
EUR 399
Description: Unconjugated

DCTN3 Polyclonal Antibody

E-AB-11144-20uL 20uL
EUR 73
Description: Unconjugated

DCTN3 Polyclonal Antibody

E-AB-11144-60uL 60uL
EUR 143
Description: Unconjugated

Dctn3 (untagged) - Mouse dynactin 3 (Dctn3), transcript variant 1, (10ug)

MC209938 10 µg Ask for price

Dctn3 (untagged) - Mouse dynactin 3 (Dctn3), transcript variant 2, (10ug)

MC209939 10 µg Ask for price

Dctn3 (Myc-DDK-tagged ORF) - Rat dynactin 3 (Dctn3), (10 ug)

RR211869 10 µg Ask for price

DCTN3 (GFP-tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 1

RG210658 10 µg Ask for price

DCTN3 (GFP-tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 2

RG201253 10 µg Ask for price

Dctn3 (GFP-tagged) - Mouse dynactin 3 (Dctn3) transcript variant 2, (10ug)

MG217276 10 µg Ask for price

Dctn3 (Myc-DDK-tagged) - Mouse dynactin 3 (Dctn3), transcript variant 2

MR217276 10 µg Ask for price

Dctn3 (Myc-DDK-tagged) - Mouse dynactin 3 (Dctn3), transcript variant 1

MR201747 10 µg Ask for price

Human DCTN3 shRNA Plasmid

20-abx957717
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Mouse DCTN3 shRNA Plasmid

20-abx974349
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DCTN3 (myc-DDK-tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 4

RC236108 10 µg Ask for price

DCTN3 (myc-DDK-tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 3

RC236149 10 µg Ask for price

DCTN3 (myc-DDK-tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 5

RC236293 10 µg Ask for price

DCTN3 (Myc-DDK-tagged)-Human dynactin 3 (p22) (DCTN3), transcript variant 2

RC201253 10 µg Ask for price

DCTN3 (Myc-DDK-tagged)-Human dynactin 3 (p22) (DCTN3), transcript variant 1

RC210658 10 µg Ask for price

DCTN3 Antibody, HRP conjugated

1-CSB-PA006566LB01HU
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

DCTN3 Recombinant Protein (Rat)

RP197492 100 ug Ask for price

DCTN3 Antibody, FITC conjugated

1-CSB-PA006566LC01HU
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

DCTN3 Recombinant Protein (Mouse)

RP128180 100 ug Ask for price

DCTN3 Recombinant Protein (Mouse)

RP128183 100 ug Ask for price

DCTN3 Recombinant Protein (Human)

RP008860 100 ug Ask for price

OACA08754-50UL - DCTN3 Antibody

OACA08754-50UL 50ul
EUR 189

OACA08755-50UL - DCTN3 Antibody

OACA08755-50UL 50ul
EUR 189

OACA02840-50UG - DCTN3 Antibody

OACA02840-50UG 50ug
EUR 179

DCTN3 Antibody, Biotin conjugated

1-CSB-PA006566LD01HU
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

OACA08754-100UL - DCTN3 Antibody

OACA08754-100UL 100ul
EUR 230

OACA08755-100UL - DCTN3 Antibody

OACA08755-100UL 100ul
EUR 230

OACA02840-100UG - DCTN3 Antibody

OACA02840-100UG 100ug
EUR 319

OAEB00956-100UG - DCTN3 Antibody

OAEB00956-100UG 100ug
EUR 349

DCTN3 Rabbit Polyclonal Antibody

E10G08223 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

DCTN3 Rabbit Polyclonal Antibody

E10G01275 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Lenti ORF clone of Dctn3 (mGFP-tagged ORF) - Rat dynactin 3 (Dctn3), (10 ug)

RR211869L4 10 µg Ask for price

Dctn3 ORF Vector (Rat) (pORF)

ORF065832 1.0 ug DNA
EUR 607.2

Dctn3 ORF Vector (Mouse) (pORF)

ORF042728 1.0 ug DNA
EUR 607.2

Dctn3 ORF Vector (Mouse) (pORF)

ORF042729 1.0 ug DNA
EUR 607.2

DCTN3 ORF Vector (Human) (pORF)

ORF002954 1.0 ug DNA
EUR 114

Human Dynactin subunit 3 (DCTN3)

1-CSB-EP006566HU
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Description: Recombinant Human Dynactin subunit 3(DCTN3) expressed in E.coli

Human DCTN3 Protein Lysate 20ug

IHUDCTN3PLLY20UG each
EUR 213
Description: Human DCTN3 Protein Lysate 20ug

Lenti ORF clone of Dctn3 (Myc-DDK-tagged ORF) - Rat dynactin 3 (Dctn3), (10 ug)

RR211869L3 10 µg Ask for price

Lenti ORF clone of Dctn3 (mGFP-tagged) - Mouse dynactin 3 (Dctn3), transcript variant 2

MR217276L4 10 µg Ask for price

Lenti ORF clone of Dctn3 (mGFP-tagged) - Mouse dynactin 3 (Dctn3), transcript variant 1

MR201747L4 10 µg Ask for price

Lenti ORF particles, Dctn3 (GFP-tagged ORF) - Rat dynactin 3 (Dctn3), 200ul, >10^7 TU/mL

RR211869L4V 200 µl Ask for price

Dynactin Subunit 3 (DCTN3) Antibody

20-abx321092
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  • 100 ul
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Dynactin Subunit 3 (DCTN3) Antibody

20-abx321093
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  • 100 ul
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Dynactin Subunit 3 (DCTN3) Antibody

abx431970-200ul 200 ul
EUR 460.8

Dynactin Subunit 3 (DCTN3) Antibody

abx431971-200ul 200 ul
EUR 343.2

Dynactin Subunit 3 (DCTN3) Antibody

20-abx301171
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  • 100 ug
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Dynactin Subunit 3 (DCTN3) Antibody

20-abx210222
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  • 100 ul
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Dynactin Subunit 3 (DCTN3) Antibody

20-abx210223
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Dynactin Subunit 3 (DCTN3) Antibody

abx149748-100ug 100 ug
EUR 526.8

Dynactin Subunit 3 (DCTN3) Antibody

abx301171-100g 100 µg
EUR 362.5

Dynactin Subunit 3 (DCTN3) Antibody

abx301171-20g 20 µg
EUR 162.5

Dynactin Subunit 3 (DCTN3) Antibody

abx301171-50g 50 µg
EUR 250

Dynactin Subunit 3 (DCTN3) Antibody

abx210222-100l 100 µl
EUR 350

Dynactin Subunit 3 (DCTN3) Antibody

abx210222-50l 50 µl
EUR 250

Dynactin Subunit 3 (DCTN3) Antibody

abx210223-100l 100 µl
EUR 350

Dynactin Subunit 3 (DCTN3) Antibody

abx210223-50l 50 µl
EUR 250

Dynactin Subunit 3 (DCTN3) Antibody

abx321092-100g 100 µg
EUR 350

Dynactin Subunit 3 (DCTN3) Antibody

abx321092-50g 50 µg
EUR 250

Dynactin Subunit 3 (DCTN3) Antibody

abx321093-100g 100 µg
EUR 350

Dynactin Subunit 3 (DCTN3) Antibody

abx321093-50g 50 µg
EUR 250

Dynactin Subunit 3 (DCTN3) Antibody

abx431970-100g 100 µg
EUR 387.5

OCOA11742-20UG - DCTN3 Protein Lysate

OCOA11742-20UG 20ug
EUR 169

OCOA02713-20UG - DCTN3 Protein Lysate

OCOA02713-20UG 20ug
EUR 169

Dctn3 rabbit polyclonal antibody, Serum

AP54900SU-N 200 µl Ask for price

DCTN3 Over-expression Lysate Product

GWB-EC87FA 0.1 mg Ask for price

DCTN3 Over-expression Lysate Product

GWB-77457A 0.1 mg Ask for price

Lenti ORF clone of Dctn3 (Myc-DDK-tagged) - Mouse dynactin 3 (Dctn3), transcript variant 2

MR217276L3 10 µg Ask for price

Lenti ORF clone of Dctn3 (Myc-DDK-tagged) - Mouse dynactin 3 (Dctn3), transcript variant 1

MR201747L3 10 µg Ask for price

Lenti ORF particles, Dctn3 (Myc-DDK-tagged ORF) - Rat dynactin 3 (Dctn3), 200ul, >10^7 TU/mL

RR211869L3V 200 µl Ask for price

DCTN3 Polyclonal Antibody, HRP Conjugated

A57038
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  • 100 µg
  • 50 ul
  • 100 ul

DCTN3 Polyclonal Antibody, FITC Conjugated

A57039
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  • 100 µg
  • 50 ul
  • 100 ul

Polyclonal DCTN3 Antibody (internal region)

APG00714G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications:

Polyclonal DCTN3 Antibody (internal region)

APG00715G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications:

OPCA01557-1MG - DCTN3 Recombinant Protein

OPCA01557-1MG 1mg
EUR 1379

OPCA01557-20UG - DCTN3 Recombinant Protein

OPCA01557-20UG 20ug
EUR 218

Human Dynactin 3 (DCTN3)ELISA Kit

201-12-2661 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Dynactin 3(DCTN3)ELISA Kit

QY-E03780 96T
EUR 433.2

Human Dynactin 3 (DCTN3)ELISA Kit

YLA1958HU-48T 48T Ask for price