Bibliometrics and Visualization of the Mechanisms of Parkinson’s Diseases based on Animal Models.

Energy metabolism disorder is one of the causes of Parkinson’s disease (PD). Rodents such as rats and mice are often used to establish animal models of PD. This paper uses bibliometric methods to analyze studies of rats and mice models of PD published between 2009 and 2018 in the Web of Science (WOS) database using software CiteSpace V.

In addition, we conducted a literature review on the status of development and research hotspots in this field in 10 articles Related years.The last in mice and rat PD models derived from the database WOS, and keyword analysis in this article is done using CiteSpace V. A timeline graph developed by software to indicate a focus of researchers in total PD field.A of 8636 articles obtained.

The results of cluster analysis in the field of PD such as nerve inflammation, oxidative stress and autophagy contributes to a systematic review of the pathogenesis of PD. At the same time, based on the properties of the drug model, this review has summarized and compared the different administration techniques and mechanisms of 6- hydroxydopamine (6-OHDA), 1-methyl-4-phenyl-1, 2, 4, 5 -tetrahydropyridine (MPTP), paraquat and rotenone.According for bibliometric analysis, the study of PD is focused on the mechanism of oxidative stress, neuroinflammation and autophagy.

Activated microglia release inflammatory cytokines; Mitochondrial dysfunction caused by oxidative damage to mitochondrial proteins; normal autophagy-lysosomal pathway can lead to abnormal protein deposition in dopaminergic neurons. In addition, although many animal models of PD have been established, there are some limitations to this model. Therefore, it is necessary to develop models that accurately mimic human PD.

DCTN3 siRNA

20-abx913699
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DCTN3 siRNA

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DCTN3 Antibody

1-CSB-PA921442
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300

DCTN3 Antibody

1-CSB-PA210409
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300

DCTN3 Antibody

1-CSB-PA006566ESR1HU
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

DCTN3 Antibody

1-CSB-PA006566ESR2HU
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  • EUR 402.00
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

DCTN3 Antibody

1-CSB-PA006566LA01HU
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  • EUR 402.00
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

DCTN3 Antibody

DF8351 200ul
EUR 420

anti-DCTN3

YF-PA17547 50 ul
EUR 435.6
Description: Mouse polyclonal to DCTN3

anti-DCTN3

YF-PA17548 50 ug
EUR 435.6
Description: Mouse polyclonal to DCTN3

DCTN3 Conjugated Antibody

C36403 100ul
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DCTN3 cloning plasmid

CSB-CL006566HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the DCTN3 gene.

DCTN3 Blocking Peptide

DF8351-BP 1mg
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Anti-DCTN3 antibody

STJ72399 100 µg
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Anti-DCTN3 antibody

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pENTR223-DCTN3 vector

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DCTN3 Polyclonal Antibody

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DCTN3 Polyclonal Antibody

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DCTN3 Polyclonal Antibody

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DCTN3 Polyclonal Antibody

A57037
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Human DCTN3 shRNA Plasmid

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Mouse DCTN3 shRNA Plasmid

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DCTN3 Antibody, HRP conjugated

1-CSB-PA006566LB01HU
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

DCTN3 Antibody, FITC conjugated

1-CSB-PA006566LC01HU
  • EUR 380.40
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

DCTN3 Antibody, Biotin conjugated

1-CSB-PA006566LD01HU
  • EUR 380.40
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

DCTN3 Recombinant Protein (Human)

RP008860 100 ug Ask for price

DCTN3 Recombinant Protein (Rat)

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DCTN3 Recombinant Protein (Mouse)

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Dynactin Subunit 3 (DCTN3) Antibody

abx149748-100ug 100 ug
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Dynactin Subunit 3 (DCTN3) Antibody

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Dynactin Subunit 3 (DCTN3) Antibody

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Dynactin Subunit 3 (DCTN3) Antibody

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Dynactin Subunit 3 (DCTN3) Antibody

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Dynactin Subunit 3 (DCTN3) Antibody

20-abx301171
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Dynactin Subunit 3 (DCTN3) Antibody

abx431970-200ul 200 ul
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Dynactin Subunit 3 (DCTN3) Antibody

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Human Dynactin subunit 3 (DCTN3)

1-CSB-EP006566HU
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Description: Recombinant Human Dynactin subunit 3(DCTN3) expressed in E.coli

Polyclonal DCTN3 Antibody (internal region)

APG00714G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications:

Polyclonal DCTN3 Antibody (internal region)

APG00715G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications:

Dctn3 ORF Vector (Rat) (pORF)

ORF065832 1.0 ug DNA
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ORF002954 1.0 ug DNA
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Dctn3 ORF Vector (Mouse) (pORF)

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DCTN3 Polyclonal Antibody, HRP Conjugated

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DCTN3 Polyclonal Antibody, HRP Conjugated

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DCTN3 Polyclonal Antibody, FITC Conjugated

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DCTN3 Polyclonal Antibody, FITC Conjugated

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DCTN3 Polyclonal Antibody, HRP Conjugated

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DCTN3 Polyclonal Antibody, FITC Conjugated

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DCTN3 Polyclonal Antibody, Biotin Conjugated

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Human Dynactin 3 (DCTN3)ELISA Kit

201-12-2661 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Dynactin Subunit 3 (DCTN3) Antibody (HRP)

20-abx303590
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  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
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  • 100 ug
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Dynactin Subunit 3 (DCTN3) Antibody (FITC)

20-abx303591
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  • EUR 2214.00
  • EUR 718.80
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  • 100 ug
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Dynactin Subunit 3 (DCTN3) Antibody (Biotin)

20-abx303592
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
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DCTN3 sgRNA CRISPR Lentivector set (Human)

K0567401 3 x 1.0 ug
EUR 406.8

Dctn3 sgRNA CRISPR Lentivector set (Rat)

K6032901 3 x 1.0 ug
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Dctn3 sgRNA CRISPR Lentivector set (Mouse)

K3108201 3 x 1.0 ug
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Human Dynactin 3(DCTN3)ELISA Kit

QY-E03780 96T
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Human Dynactin 3 (DCTN3)ELISA Kit

YLA1958HU-48T 48T
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Human Dynactin 3 (DCTN3)ELISA Kit

YLA1958HU-96T 96T
EUR 562.5

Mouse Dynactin subunit 3, Dctn3 ELISA KIT

ELI-26362m 96 Tests
EUR 1038

Bovine Dynactin subunit 3, DCTN3 ELISA KIT

ELI-26525b 96 Tests
EUR 1113.6

Human Dynactin subunit 3, DCTN3 ELISA KIT

ELI-08944h 96 Tests
EUR 988.8

DCTN3 sgRNA CRISPR Lentivector (Human) (Target 1)

K0567402 1.0 ug DNA
EUR 184.8

DCTN3 sgRNA CRISPR Lentivector (Human) (Target 2)

K0567403 1.0 ug DNA
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DCTN3 sgRNA CRISPR Lentivector (Human) (Target 3)

K0567404 1.0 ug DNA
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Dctn3 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6032902 1.0 ug DNA
EUR 184.8

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K6032903 1.0 ug DNA
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K6032904 1.0 ug DNA
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Dctn3 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3108202 1.0 ug DNA
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K3108204 1.0 ug DNA
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DCTN3 Protein Vector (Human) (pPB-C-His)

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DCTN3 Protein Vector (Human) (pPM-C-HA)

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DCTN3 Protein Vector (Mouse) (pPB-C-His)

PV170910 500 ng
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DCTN3 Protein Vector (Mouse) (pPB-N-His)

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DCTN3 Protein Vector (Mouse) (pPM-C-HA)

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DCTN3 Protein Vector (Mouse) (pPM-C-His)

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DCTN3 Protein Vector (Mouse) (pPB-C-His)

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DCTN3 Protein Vector (Mouse) (pPB-N-His)

PV170915 500 ng
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DCTN3 Protein Vector (Mouse) (pPM-C-HA)

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DCTN3 Protein Vector (Mouse) (pPM-C-His)

PV170917 500 ng
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DCTN3 3'UTR Luciferase Stable Cell Line

TU005639 1.0 ml
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Dctn3 3'UTR GFP Stable Cell Line

TU253211 1.0 ml Ask for price

Dctn3 3'UTR Luciferase Stable Cell Line

TU104917 1.0 ml Ask for price

DCTN3 3'UTR GFP Stable Cell Line

TU055639 1.0 ml
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Dctn3 3'UTR Luciferase Stable Cell Line

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DCTN3 Protein Vector (Rat) (pPB-C-His)

PV263326 500 ng
EUR 723.6

DCTN3 Protein Vector (Rat) (pPB-N-His)

PV263327 500 ng
EUR 723.6

DCTN3 Protein Vector (Rat) (pPM-C-HA)

PV263328 500 ng
EUR 723.6

DCTN3 Protein Vector (Rat) (pPM-C-His)

PV263329 500 ng
EUR 723.6

DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0567405 3 x 1.0 ug
EUR 451.2

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K6032905 3 x 1.0 ug
EUR 451.2

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3108205 3 x 1.0 ug
EUR 451.2

DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0567406 1.0 ug DNA
EUR 200.4

DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0567407 1.0 ug DNA
EUR 200.4

DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0567408 1.0 ug DNA
EUR 200.4

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K6032906 1.0 ug DNA
EUR 200.4

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K6032907 1.0 ug DNA
EUR 200.4

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K6032908 1.0 ug DNA
EUR 200.4

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3108206 1.0 ug DNA
EUR 200.4

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3108207 1.0 ug DNA
EUR 200.4

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3108208 1.0 ug DNA
EUR 200.4