Bibliometrics and Visualization of the Mechanisms of Parkinson’s Diseases based on Animal Models.

Energy metabolism disorder is one of the causes of Parkinson’s disease (PD). Rodents such as rats and mice are often used to establish animal models of PD. This paper uses bibliometric methods to analyze studies of rats and mice models of PD published between 2009 and 2018 in the Web of Science (WOS) database using software CiteSpace V.

In addition, we conducted a literature review on the status of development and research hotspots in this field in 10 articles Related years.The last in mice and rat PD models derived from the database WOS, and keyword analysis in this article is done using CiteSpace V. A timeline graph developed by software to indicate a focus of researchers in total PD field.A of 8636 articles obtained.

The results of cluster analysis in the field of PD such as nerve inflammation, oxidative stress and autophagy contributes to a systematic review of the pathogenesis of PD. At the same time, based on the properties of the drug model, this review has summarized and compared the different administration techniques and mechanisms of 6- hydroxydopamine (6-OHDA), 1-methyl-4-phenyl-1, 2, 4, 5 -tetrahydropyridine (MPTP), paraquat and rotenone.According for bibliometric analysis, the study of PD is focused on the mechanism of oxidative stress, neuroinflammation and autophagy.

Activated microglia release inflammatory cytokines; Mitochondrial dysfunction caused by oxidative damage to mitochondrial proteins; normal autophagy-lysosomal pathway can lead to abnormal protein deposition in dopaminergic neurons. In addition, although many animal models of PD have been established, there are some limitations to this model. Therefore, it is necessary to develop models that accurately mimic human PD.

DCTN3 Antibody

1-CSB-PA921442
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300

DCTN3 Antibody

36403-100ul 100ul
EUR 252

DCTN3 siRNA

20-abx913699
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DCTN3 siRNA

20-abx913700
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DCTN3 Antibody

ABD8351 100 ug
EUR 438

DCTN3 Antibody

DF8351 200ul
EUR 304
Description: DCTN3 Antibody detects endogenous levels of total DCTN3.

anti-DCTN3

YF-PA17547 50 ul
EUR 363
Description: Mouse polyclonal to DCTN3

anti-DCTN3

YF-PA17548 50 ug
EUR 363
Description: Mouse polyclonal to DCTN3

DCTN3 Peptide

42-330P 0.1 mg
EUR 338
Description: (IN) DCTN3 Peptide

DCTN3 Peptide

42-682P 0.1 mg
EUR 338
Description: (IN) DCTN3 Peptide

DCTN3 cloning plasmid

CSB-CL006566HU-10ug 10ug
EUR 233
Description: A cloning plasmid for the DCTN3 gene.

DCTN3 Polyclonal Antibody

A57037 100 µg
EUR 570.55
Description: The best epigenetics products

Anti-DCTN3 antibody

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Anti-DCTN3 antibody

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DCTN3 Blocking Peptide

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DCTN3 Antibody, HRP conjugated

1-CSB-PA006566LB01HU
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  • 100ug
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

DCTN3 Antibody, FITC conjugated

1-CSB-PA006566LC01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

DCTN3 Antibody, Biotin conjugated

1-CSB-PA006566LD01HU
  • EUR 317.00
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Description: A polyclonal antibody against DCTN3. Recognizes DCTN3 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Mouse DCTN3 shRNA Plasmid

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Human DCTN3 shRNA Plasmid

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DCTN3 Recombinant Protein (Mouse)

RP128180 100 ug Ask for price

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  • 100ug
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  • 200ug
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Description: Recombinant Human Dynactin subunit 3(DCTN3) expressed in E.coli

Polyclonal DCTN3 Antibody (internal region)

APG00714G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications:

Polyclonal DCTN3 Antibody (internal region)

APG00715G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human DCTN3 (internal region). This antibody is tested and proven to work in the following applications:

Dynactin Subunit 3 (DCTN3) Antibody

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  • 100 ul
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Dynactin Subunit 3 (DCTN3) Antibody

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DCTN3 Polyclonal Antibody, HRP Conjugated

A57038 100 µg
EUR 570.55
Description: kits suitable for this type of research

DCTN3 Polyclonal Antibody, FITC Conjugated

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Description: fast delivery possible

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EUR 570.55
Description: reagents widely cited

Dynactin Subunit 3 (DCTN3) Antibody

abx431970-200ul 200 ul
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Dynactin Subunit 3 (DCTN3) Antibody

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Dynactin Subunit 3 (DCTN3) Antibody

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Dynactin Subunit 3 (DCTN3) Antibody

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Human Dynactin 3 (DCTN3)ELISA Kit

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EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Dynactin Subunit 3 (DCTN3) Antibody (HRP)

20-abx303590
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Dynactin Subunit 3 (DCTN3) Antibody (FITC)

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Dynactin Subunit 3 (DCTN3) Antibody (Biotin)

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QY-E03780 96T
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Dctn3 sgRNA CRISPR Lentivector set (Mouse)

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Dctn3 sgRNA CRISPR Lentivector (Mouse) (Target 1)

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DCTN3 sgRNA CRISPR Lentivector (Human) (Target 1)

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K6032902 1.0 ug DNA
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K6032903 1.0 ug DNA
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DCTN3 Protein Vector (Human) (pPB-C-His)

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EUR 329

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Dctn3 3'UTR Luciferase Stable Cell Line

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DCTN3 Protein Vector (Mouse) (pPB-C-His)

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TU055639 1.0 ml
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Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3108205 3 x 1.0 ug
EUR 376

DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0567405 3 x 1.0 ug
EUR 376

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K6032905 3 x 1.0 ug
EUR 376

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3108206 1.0 ug DNA
EUR 167

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3108207 1.0 ug DNA
EUR 167

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3108208 1.0 ug DNA
EUR 167

DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0567406 1.0 ug DNA
EUR 167

DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0567407 1.0 ug DNA
EUR 167

DCTN3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0567408 1.0 ug DNA
EUR 167

Dctn3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K6032906 1.0 ug DNA
EUR 167